KUÇI MIMOZA1*, REXHA TEFTA2
1Clinical and Biochemical Laboratory, Hospital Center of Elbasan, Elbasan, Albania
2Department of Biology,Faculty of Natyral Science, University of Tirana, Tirana, Albania
*Corresponding author email: kuci_mimoza@yahoo.com;
Abstract
The risk of developing coronary heart diseases and atherosclerosis increases as the total cholesterol level increases and HDL cholesterol level decreases. Atherosclerosis can affect the arteries that supply blood to the heart (coronary artery disease), those that supply blood to the brain (cerebrovascular disease). The role of high levels of total cholesterol and LDL cholesterol and the protective role of HDL cholesterol in coronary artery diseases and atherosclerosis, links between them and family history with coronary artery diseases or dislipidemia, diabetes, obesity is analyzed in this study. A sample population consisting of 300 persons from Elbasan district, selected at random, was taken into examination. They were examined about blood analyses for the level of: triglycerides, total cholesterol, HDL-cholesterol and the level of LDL-cholesterol. The analysis of contingent tables and the determination of Hi squares is used to see the association between variables. A low level of HDL cholesterol and a high level of LDL-cholesterol increase the risk of cardiovascular disease. The persons suffering from the diabetes, or who had a family history with dislipidemia are more likely to be affected by the coronary heart diseases. Women are characterized by higher values of HDL-cholesterol (45.4mg/dl ± 8.2) than men (40.5mg/dl ± 8.7), therefore are more protected from coronary heart diseases. Between level of HDL-cholesterol and gender has a high association (χ2 square = 30,567 df = 1). Increased triglyceride level is associated with reduced levels of HDL-cholesterol χ2 = 4.963 (df = 1) and increased levels of total cholesterol χ2 = 6.053 (df = 1).
Keywords: HDL cholesterol, coronary heart disease, total cholesterol, atherosclerosis.
